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. 2011 Jul 21;60(12):1739–1750. doi: 10.1007/s00262-011-1069-4

Fig. 6.

Fig. 6

IL-17 has no effect on the GL261-glioma formation. a MRI 7 T images on a frontal plane. T2 (Left) and T1 after contrast medium (Right) images on day 8 after GL261 implantation performed on a wild-type (WT) and IL-17 KO (KO) mouse show a similar tumor engraftment. b Brain pictures of wt and IL-17 KO 12 days after tumor implantation (Upper) and Ki-67 staining (magnification 40×, Lower) show a similar proliferation ratio in wt and IL-17 KO mice. c MRI 7 T images on a frontal plane. T2 (Left) and T1 after contrast medium (Right) images 16 after GL261 implantation performed on a wild-type and IL-17 KO mouse. d Kaplan–Meier analysis curves represent the survival time (in days) of IL-17 KO compared to WT mice injected ic with GL261 cells. All mice died by day 29. The median survival of IL-17 KO was 27 days (n = 5, mean ± SD is 26.8 ± 2.2); the median of WT mice was 26.5 (n = 5, mean ± SD is 26.8 ± 1.7) (P = 0.9)