Fig. 4.

Inhibition of tumor growth in vivo following endostatin treatment. a, b Images of mice after killing at day 15. c Endostatin protein expression in tumors as determined by ELISA. d The tumor index for each treatment group as measured on the final day of in vivo experimentation. e Tumor growth index values for each treatment group recorded over the 15-day study period. Tumors were measured on every third day. Data are mean ± SD from three independent experiments. *p < 0.05 versus control group; ^# p < 0.05 versus PQ group, ^Δp < 0.05 versus SL/pScramble group