Fig. 3.

CD163+CD14+ cells in pleural effusion or peripheral blood from malignant or non-malignant patients. a CD163+CD14+ cells derived from pleural effusion and peripheral blood were detected in lung cancer patients and non-malignant patients by using flow cytometry. One representative analysis from MPE and NMPE cases is shown. b Comparison of CD163+CD14+ cell frequency in MPE and NMPE was performed. Results are presented as a scatter diagram. c The percentage of CD163+CD14+ cells in pleural effusion or peripheral blood from malignant or non-malignant patients. Results presented as histogram. d ROC analysis of CD163+CD14+ cell frequency in MPE with an AUC of 0.941 (P < 0.001). e Using a cutoff level of 3.65 %, CD163+CD14+ cell frequency-based MPE diagnosis for cancer patients had a sensitivity of 86 % and a specificity of 100 %