Fig. 4.

Blinded validation study of CD163+CD14+ macrophages in MPE. a Phenotype analysis of CD163+CD14+ macrophages obtained from MPE and NMPE was performed. One representative analysis from MPE and NMPE cases is shown. b Comparison of CD163+CD14+ cell frequency in MPE and NMPE was performed. Results presented as a scatter diagram. c ROC analysis of CD163+CD14+ cell frequency was performed with an AUC of 0.862 (P < 0.001). d Using a cutoff level of 1.70 %, a specificity of 100 % and a sensitivity of 78.9 % were achieved