Fig. 3.

PCL and BLP inhibit proliferation, induce apoptosis and enhance the migratory capacity of BMDM. a Phenotypic appearance of BMDM after incubation with PBS, PCL or BLP for 72 h. b Metabolic activity of PBS-, PCL- or BLP-treated BMDM as measured by a WST-1 assay. Values of solvent-treated controls were set to 100 %. c BrdU incorporation shown as percentage of respective solvent-treated controls and d Annexin V⁺ cells after treatment with PBS, PCL or BLP for 72 h. e Migratory capacity of BMDM shown as percentage of the values obtained with solvent-treated controls. Data represent mean ± SEM of at least three independent experiments as performed in duplicates. * p < 0.05 by Mann–Whitney U testing