Table 1.

Demographics and disease characteristics

	Total N = 391	Utah n = 176	Michigan n = 215
Age
Years of age, median (IQR)	55 (49–59)	55 (49–60)	55 (49–59)
Sex
Males, n (%)	294 (75 %)	140 (80 %)	154 (72 %)
Prior therapy, n (%)
Nephrectomy	328 (84 %)	148 (92 %)	180 (84 %)
Number of metastatic disease sites, n (%)
1	118 (30 %)	52 (30 %)	66 (31 %)
2	133 (34 %)	62 (35 %)	71 (33 %)
3	85 (22 %)	36 (20 %)	49 (23 %)
≥4	48 (12 %)	19 (11 %)	29 (13 %)
Unknown	7 (2 %)	7 (4 %)	0
Common sites of metastases, n (%)
Lung	289 (74 %)	118 (69 %)	171 (80 %)
Bone	116 (30 %)	68 (40 %)	48 (22 %)
Lymph node	115 (29 %)	37 (22 %)	78 (36 %)
Liver	61 (16 %)	28 (16 %)	33 (15 %)
Brain	22 (6 %)	17 (10 %)	5 (2 %)
IMDC risk categories, n (%)
Favorable	80 (20 %)	36 (20 %)	44 (20 %)
Intermediate	251 (64 %)	109 (62 %)	142 (66 %)
Poor	60 (15 %)	31 (18 %)	29 (13 %)

IMDC International Metastatic Renal Cell Carcinoma Database Consortium