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. 2015 Dec 11;65(2):127–139. doi: 10.1007/s00262-015-1772-7

Table 2.

Summary of median time to tumor progression (TTP) (days), median survival (days) and fraction long-term survival for 15 Gy RT only, 15 Gy RT plus IT, 18.75 Gy RT only, 18.75 Gy RT plus IT, 22.5 Gy RT only, and 22.5 Gy RT plus IT

Untreated control
(N = 7)
15 Gy
R
ALL
(N = 20)
15 Gy
R + I
ALL
(N = 18)
p 18.75 Gy R
ALL
(N = 10)
18.75 Gy
R + I
ALL
(N = 9)
p 22.5 Gy
R
ALL
(N = 8)
22.5 Gy
R + I
ALL
(N = 9)
Median time to tumor progression (TTP) (days) N/A

13.5

(7–28)

20

(13–34)

0.013 19 28 0.006 40D, 47D, 140D ~230D
Median survival (days) 15

44

(22–360)

59

(41–93)

0.0098 43 58 0.0056 Median not reached Median not reached
Fraction long-term survivors 0 1/20 0/18 0/10 2/9 5/8 8/9

For 22.5 Gy, median survival was not reached. TTP for the three mice that died of brain tumors are listed