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. 2017 May 18;66(10):1265–1273. doi: 10.1007/s00262-017-2018-7

Table 1.

Characteristics of glioma patients and controls

Clinical features Glioma cases Controls P b
All A*02:01 (+) A*02:01 (−) P a All A*02:01 (+) A*02:01 (−) P a
No. % No. % No. % No. % No. % No. %
Total 150 100 24 16 126 84 150 100 49 32.7 101 67.3 0.001
Age 0.509
 Mean 47.4 43.8 47.0 0.208 46.5 49.6 46.4 0.139
 SD 12.3 9.7 11.6 11.4 13.0 12.0
Sex
 Male 85 56.7 15 62.5 70 55.6 0.529 85 56.7 29 59.2 56 55.4 0.665
 Female 65 43.3 9 37.5 56 44.4 65 43.3 20 40.8 45 44.6
Gliomas
 Low-grade 33 22 5 20.8 28 22.2 0.880
 High-grade 117 78 19 79.2 98 77.8
IDH1/2
 Mutated 51 34 9 37.5 42 33.3 0.693
 Wild-type 99 66 15 62.5 84 66.7
MGMT
 Methylated 59 39.3 11 45.8 48 38.1 0.477
 Unmethylated 91 60.7 13 54.2 78 61.9
IE1-72
 Positive 117 78 6 25 111 88.1 0.001
 Negative 33 22 18 75 15 11.9
pp65
 Positive 99 66 6 25 93 73.8 0.001
 Negative 51 44 18 75 33 26.2
HCMV DNA
 Positive 48 32 2 8.3 46 36.5 0.007
 Negative 102 68 22 91.7 80 63.5
HCMV IgG 0.602
 Positive 112 74.7 15 62.5 97 77.0 0.135 108 72.0 32 65.3 76 75.2 0.203
 Negative 38 25.3 9 37.5 29 23.0 42 28.0 17 34.7 25 24.8
HCMV IgM 0.442
 Positive 28 18.7 1 4.2 27 21.4 0.047 23 15.3 3 6.1 20 19.8 0.029
 Negative 122 81.3 23 95.8 99 78.6 127 84.7 46 93.9 81 80.2

Statistically significant P values <0.05 are italicized

aA*02:01 (+) vs A*02:01 (−)

bCases vs controls