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. 2016 Dec 3;66(3):343–354. doi: 10.1007/s00262-016-1931-5

Table 1.

Correlation between AMC and CD68+ TAM and clinicopathological characteristics

No. of patients % AMC CD68+ TAM
Low High p Low High p
Age (years) 0.472 0.170
 ≤60 124 56.36 65 59 109 15
 >60 96 43.64 55 41 78 18
Gender 0.554 0.558
 Male 117 53.18 66 51 101 16
 Female 103 46.82 54 49 86 17
KPS 0.322 0.833
 <80 61 27.73 30 31 51 10
 ≥80 159 72.27 90 69 136 23
Tumor location 0.745 0.061
 Upper 26 11.82 15 11 22 4
 Middle 88 40.00 50 38 69 19
 Lower 106 48.18 55 51 96 10
Tumor differentiation 0.001 0.886
 Well 88 40.00 52 36 76 12
 Moderate 84 38.18 53 31 71 13
 Poor 48 21.82 15 33 40 8
Tumor length 0.019 0.022
 ≤4 cm 133 60.45 81 52 119 14
 >4 cm 87 39.54 39 48 68 19
Perineural invasion 1.000 0.222
 No 214 97.27 117 97 183 31
 Yes 6 2.73 3 3 4 2
Vascular invasion 0.250 0.011
 No 213 96.82 118 95 184 29
 Yes 7 3.18 2 5 3 4
Treatment 0.550 0.304
 Surgery only 102 46.36 51 51 91 11
 Adjuvant chemotherapy 46 20.91 25 21 39 7
 Adjuvant radiation 39 17.73 24 15 31 8
 Adjuvant chemoradiation 33 15.00 20 13 26 7
Recurrence 1.000 0.466
 No 38 17.27 21 17 34 4
 Yes 182 82.73 99 83 153 29

Values in bold signify p < 0.05

AMC absolute monocyte count, TAM tumor-associated macrophages