Table 1.
No. of patients | % | AMC | CD68+ TAM | |||||
---|---|---|---|---|---|---|---|---|
Low | High | p | Low | High | p | |||
Age (years) | 0.472 | 0.170 | ||||||
≤60 | 124 | 56.36 | 65 | 59 | 109 | 15 | ||
>60 | 96 | 43.64 | 55 | 41 | 78 | 18 | ||
Gender | 0.554 | 0.558 | ||||||
Male | 117 | 53.18 | 66 | 51 | 101 | 16 | ||
Female | 103 | 46.82 | 54 | 49 | 86 | 17 | ||
KPS | 0.322 | 0.833 | ||||||
<80 | 61 | 27.73 | 30 | 31 | 51 | 10 | ||
≥80 | 159 | 72.27 | 90 | 69 | 136 | 23 | ||
Tumor location | 0.745 | 0.061 | ||||||
Upper | 26 | 11.82 | 15 | 11 | 22 | 4 | ||
Middle | 88 | 40.00 | 50 | 38 | 69 | 19 | ||
Lower | 106 | 48.18 | 55 | 51 | 96 | 10 | ||
Tumor differentiation | 0.001 | 0.886 | ||||||
Well | 88 | 40.00 | 52 | 36 | 76 | 12 | ||
Moderate | 84 | 38.18 | 53 | 31 | 71 | 13 | ||
Poor | 48 | 21.82 | 15 | 33 | 40 | 8 | ||
Tumor length | 0.019 | 0.022 | ||||||
≤4 cm | 133 | 60.45 | 81 | 52 | 119 | 14 | ||
>4 cm | 87 | 39.54 | 39 | 48 | 68 | 19 | ||
Perineural invasion | 1.000 | 0.222 | ||||||
No | 214 | 97.27 | 117 | 97 | 183 | 31 | ||
Yes | 6 | 2.73 | 3 | 3 | 4 | 2 | ||
Vascular invasion | 0.250 | 0.011 | ||||||
No | 213 | 96.82 | 118 | 95 | 184 | 29 | ||
Yes | 7 | 3.18 | 2 | 5 | 3 | 4 | ||
Treatment | 0.550 | 0.304 | ||||||
Surgery only | 102 | 46.36 | 51 | 51 | 91 | 11 | ||
Adjuvant chemotherapy | 46 | 20.91 | 25 | 21 | 39 | 7 | ||
Adjuvant radiation | 39 | 17.73 | 24 | 15 | 31 | 8 | ||
Adjuvant chemoradiation | 33 | 15.00 | 20 | 13 | 26 | 7 | ||
Recurrence | 1.000 | 0.466 | ||||||
No | 38 | 17.27 | 21 | 17 | 34 | 4 | ||
Yes | 182 | 82.73 | 99 | 83 | 153 | 29 |
Values in bold signify p < 0.05
AMC absolute monocyte count, TAM tumor-associated macrophages