Table 2.
LMR | CD45RO/CD68 ratio | CD8/CD68 ratio | CD4/CD68 ratio | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Low | High | p | Low | High | p | Low | High | p | Low | High | p | |
Age (years) | 0.787 | 0.250 | 0.683 | 0.455 | ||||||||
≤60 | 72 | 52 | 87 | 37 | 98 | 26 | 97 | 27 | ||||
>60 | 54 | 42 | 74 | 22 | 78 | 18 | 79 | 17 | ||||
Gender | 0.998 | 0.303 | 0.893 | 0.636 | ||||||||
Male | 67 | 50 | 89 | 28 | 94 | 23 | 95 | 22 | ||||
Female | 59 | 44 | 72 | 31 | 82 | 21 | 81 | 22 | ||||
KPS | 0.216 | 0.253 | 0.651 | 0.407 | ||||||||
<80 | 39 | 22 | 48 | 13 | 50 | 11 | 51 | 10 | ||||
≥80 | 87 | 72 | 113 | 46 | 126 | 33 | 125 | 34 | ||||
Tumor location | 0.896 | 0.382 | 0.054 | 0.464 | ||||||||
Upper | 16 | 10 | 21 | 5 | 21 | 5 | 23 | 3 | ||||
Middle | 50 | 38 | 67 | 21 | 77 | 11 | 71 | 17 | ||||
Lower | 60 | 46 | 73 | 33 | 78 | 28 | 82 | 24 | ||||
Tumor differentiation | 0.016 | 0.006 | 0.248 | 0.036 | ||||||||
Well | 44 | 44 | 54 | 34 | 67 | 21 | 64 | 24 | ||||
Moderate | 46 | 38 | 67 | 17 | 72 | 12 | 74 | 10 | ||||
Poor | 36 | 12 | 40 | 8 | 37 | 11 | 38 | 10 | ||||
Tumor length | 0.023 | 0.300 | 0.629 | 0.408 | ||||||||
≤4 cm | 68 | 65 | 94 | 39 | 105 | 28 | 104 | 29 | ||||
>4 cm | 58 | 29 | 67 | 20 | 71 | 16 | 72 | 15 | ||||
Perineural invasion | 0.702 | 0.195 | 0.602 | 1.000 | ||||||||
No | 123 | 91 | 155 | 59 | 170 | 44 | 171 | 43 | ||||
Yes | 3 | 3 | 6 | 0 | 6 | 0 | 5 | 1 | ||||
Vascular invasion | 0.701 | 0.194 | 0.349 | 0.349 | ||||||||
No | 121 | 92 | 154 | 59 | 169 | 44 | 169 | 44 | ||||
Yes | 5 | 2 | 7 | 0 | 7 | 0 | 7 | 0 | ||||
Treatment | 0.820 | 0.178 | 0.161 | |||||||||
Surgery only | 61 | 41 | 77 | 25 | 85 | 17 | 84 | 18 | 0.330 | |||
Adjuvant chemotherapy | 25 | 21 | 30 | 16 | 32 | 14 | 37 | 9 | ||||
Adjuvant radiation | 23 | 16 | 26 | 13 | 30 | 9 | 27 | 12 | ||||
Adjuvant chemoradiation | 17 | 16 | 28 | 5 | 29 | 4 | 28 | 5 | ||||
Recurrence | 0.319 | <0.001 | 0.130 | 0.016 | ||||||||
No | 19 | 19 | 19 | 19 | 27 | 11 | 25 | 13 | ||||
Yes | 107 | 75 | 142 | 40 | 149 | 33 | 151 | 31 |
Values in bold signify p < 0.05
LMR lymphocyte-to-monocyte ratio, TILs tumor-infiltrating lymphocytes, TAM tumor-associated macrophages