Table 1.
Factor | Category | N | % |
---|---|---|---|
Age | ≤50 years | 5 | 33.3 |
>50 years | 4 | 26.7 | |
>60 years | 2 | 13.3 | |
>70 years | 4 | 26.7 | |
Gender | Male | 9 | 60.0 |
Female | 6 | 40.0 | |
M category | M1a | 6 | 40.0 |
M1b | 2 | 13.3 | |
M1c | 7 | 46.7 | |
Prior systemic treatments for metastatic disease | BRAF inhibitor/MEK inhibitor | 6 | 40.0 |
Chemotherapy | 11 | 73.3 | |
Treatment line | Second line | 15 | 100 |
Third line | 2 | 13.3 | |
Presence of brain metastasis | Yes | 0 | 0 |
No | 15 | 100 | |
Subsequent treatments | None | 8 | 53.3 |
PD-1antibody/PD-L1antibody | 2 | 13.3 | |
BRAF inhibitor/MEK inhibitor | 4 | 26.7 | |
Chemotherapy | 4 | 26.7 | |
ECOG | 0 | 14 | 6.7 |
1 | 1 | 93.3 | |
IL-2 doses | 8 | 12 | 80.0 |
7 | 2 | 13.3 | |
5 | 1 | 6.7 | |
Ipilimumab doses | 4 | 11 | 73.3 |
3 | 1 | 6.7 | |
2 | 2 | 13.3 | |
1 | 1 | 6.7 | |
LDH | Elevated | 8 | 53.3 |
Normal | 7 | 46.7 |
ECOG eastern cooperative oncology group, IL-2 interleukin-2, LDH lactate dehydrogenase, PD-1 programmed death-1, PD-L1 programmed death ligand-1