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. 2016 Dec 22;66(4):441–449. doi: 10.1007/s00262-016-1944-0

Table 1.

Baseline characteristics

Factor Category N %
Age ≤50 years 5 33.3
>50 years 4 26.7
>60 years 2 13.3
>70 years 4 26.7
Gender Male 9 60.0
Female 6 40.0
M category M1a 6 40.0
M1b 2 13.3
M1c 7 46.7
Prior systemic treatments for metastatic disease BRAF inhibitor/MEK inhibitor 6 40.0
Chemotherapy 11 73.3
Treatment line Second line 15 100
Third line 2 13.3
Presence of brain metastasis Yes 0 0
No 15 100
Subsequent treatments None 8 53.3
PD-1antibody/PD-L1antibody 2 13.3
BRAF inhibitor/MEK inhibitor 4 26.7
Chemotherapy 4 26.7
ECOG 0 14 6.7
1 1 93.3
IL-2 doses 8 12 80.0
7 2 13.3
5 1 6.7
Ipilimumab doses 4 11 73.3
3 1 6.7
2 2 13.3
1 1 6.7
LDH Elevated 8 53.3
Normal 7 46.7

ECOG eastern cooperative oncology group, IL-2 interleukin-2, LDH lactate dehydrogenase, PD-1 programmed death-1, PD-L1 programmed death ligand-1