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. 2015 Nov 26;65(1):47–59. doi: 10.1007/s00262-015-1774-5

Table 4.

Immunohistological analysis of HLA expression in tumors (T) versus matching normal epithelium (N)

Sample HLA-I B2M Heavy chain Locus A Locus B HLA-DR
12241 N ++ +++ +++ +++ +++ ++
12241 T
8723 N ++ ++ ++ ++ ±
8723 T +
9238 N ++ ++ ++ ++ ± ±
9238 T ± ± ± ± ±
8722 N ++ +++ ++ ++ ++ ±
8722 T ± ± ±
2489 N ++ ++ ++ ++ ++ ++
2489 T +++ +++ ++ ± ±
10216 N ++ ++ ++ ++ ++ ±
10216 T ++ ++ ++ ++ ++ ±

+ weakly positive, ++ positive, +++ strongly positive, ± heterogeneous, negative