Table 5.

Constitutive and IFN-γ inducible cell surface HLA expression and genomic typing of prostate cell lines

HLA expression was measured by flow cytometry in baseline conditions and after incubation with IFN-γ using several antibodies directed against different HLA specificities. MFI has been normalized using an isotype control

– no expression (MFI 0–1), + weak expression (MFI 1–10), ++ strong expression (MFI 10–100), +++ very strong expression (MFI > 100)

↑ IFN-γ-induced HLA upregulation, = resistance to IFN-γ, no HLA upregulation, ND not done

(N)—cells derived from normal prostatic epithelium of PC patients

(T)—cells derived from malignant prostatic epithelium of PC patients