Table 8.

Difference between proportions for dorsal-ventral differences in striosomes at HD-0 and HD-1, and matrix at HD-0 and HD-1

Total counts (number of fields counted) corrected counts*
	Control	HD-0	HD-1
Dorsal striosomes	287 (10) 287	183 (14) 131	78 (12) 65
Ventral striosomes	422 (17) 248	260 (13) 200	143 (13) 110
z-test: HD-0/control, dorsal versus ventral striosomes: z = 8.31, p < 0.0001, 95% confidence interval for difference between proportions: 0.268–0.424.
z-test: HD-1/control, dorsal versus ventral striosomes: z = 5.34, p < 0.0001, 95% confidence interval for difference between proportions: 0.135–0.296.

	Control	HD-0	HD-1
Dorsal matrix	913 (30) 913	896 (42) 640	536 (30) 536
Ventral matrix	1026 (51) 1026	1327 (39) 1021	943 (34) 832
95% confidence interval for the difference between proportions, HD-0/control, dorsal versus ventral matrix: 0.240–0.349 (z-test not possible for ventral matrix).
z-test: HD-1/control, dorsal versus ventral matrix: z = 10.79, p < 0.0001, 95% confidence interval for the difference between proportions: 0.183–0.264.

^*The total SPN number in all counted 40× fields is corrected to account for the different numbers of 40× fields examined.

mat, matrix; SPN, striatal projection neurons; strio, striosomes.