Table 2.
DA3 tumorsa | CT-26 tumorsb | |||||
---|---|---|---|---|---|---|
Days after rechallenge | 4 | 9 | 16 | 7 | 21 | 35 |
DaRT | 77 % | 27 % | 15 % | 100 % | 88 % | 67 % |
Inert | 62 % | 4 % | 0 % | 78 % | 56 | 34 % |
Surgery | 65 % | 0 % | 0 % | 100 % | 57 | 43 % |
Naïve | 69 % | 8 % | 4 % | 0 % | 0 % | 0 % |
DA3 or CT-26 primary tumors were treated by DaRT followed by surgery, inert + surgery or surgery alone. Three weeks after wire insertion, the mice were rechallenged with a tumorigenic dose of tumor cells and tumor development was monitored
aDA3 rechallenge was injected s.c. to 24–26 animals/group for each treatment
bCT-26 rechallenge was injected s.c. to 7–9 animals/group for each treatment