Fig. 4.

Effects of the MJ7-Ngb immunotoxin on male C57BL/6 J mice bearing a palpable B16MEL4A5 mouse melanoma tumour. C57BL/6 J mice were injected with a suspension of 1.25 × 10⁵ mouse B16MEL4A5 melanoma cells into the right flank, and tumour development and evolution were assessed by measuring their volume. The different treatments were initiated when the tumours became measurable