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. 2011 Apr 26;60(7):1047–1055. doi: 10.1007/s00262-011-1017-3

Table 1.

Correlation between clinical parameters and B7-H4 expression

Clinical parameters Cases B7-H4 Expression
Low High P value
n % n %
Gender
 Male 80 38 47.5 42 52.5 0.0288
 Female 32 8 25.0 24 75.0
Age (years)
 <60 68 27 39.7 41 60.3 0.7150
 ≥60 44 19 43.2 25 56.8
Tumor size (cm)
 ≤4 43 20 46.5 23 53.5 0.3556
 >4 69 26 37.7 43 62.3
Tumor (T) statusa
 pT1 13 9 69.2 4 30.8 0.0871b
 pT2 50 20 40.0 30 60.0
 pT3 38 13 34.2 25 65.8
 pT4 11 4 36.4 7 63.6
Nodal (N) statusc
 N0 61 30 49.2 31 50.8 0.0564
 N1 51 16 31.4 35 68.6
Distant metastasis (M)d
 M0 96 43 44.8 53 55.2 0.0500
 M1 16 3 18.8 13 81.2
TNM stage
 I 13 9 69.2 4 30.8 0.0258 b
 II 63 25 39.7 38 60.3
 III 20 9 45.0 11 55.0
 IV 16 3 18.8 13 81.2
Total 112

Values in bold signify P < 0.05

aTumor status is classified as follows: pT1 invasion of lamina propria or submucosa, pT2 invasion of muscularis propria, pT3 invasion of adventitia, and pT4 invasion of adjacent structures

bChi-square test for trend

cNodal status is classified as follows: N0 no regional lymph-node metastasis, N1 regional lymph-node metastasis

dDistant metastasis is classified as follows: M0 no distant metastasis, M1 metastasis to cervical nodes, celiac nodes, and other distant metastases