Fig. 2.

HBV reactivation after RT does not correlate with severe RILDs in TLR4⁻ mice. a Liver HE staining analysis. Magnification, × 100. Only scattered neutrophil infiltration (arrows) was observed in livers of TLR4⁻ mice with or without HBV infection after RT. b RILD score. Mean RILD score of TLR4⁻ mice with HBV reactivation, after liver RT, was not significantly higher than in mice of the other three groups (P > 0.05). Abbreviations: TLR4 ⁻ toll-like receptor 4 mutation, HBV hepatitis B virus, RILD radiation-induced liver disease, HE hematoxylin and eosin, RT radiotherapy