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Increased survival of mice treated with combined cryoimmunotherapy. Mice were inoculated i.f.p. with D122-luc-5.5 and then treated as described in materials and methods. a Tumor growth kinetics measured with calipers (tumor volume, mm3). b Post-surgical survival of mice treated with different protocols. Combined results of five independent experiments (n = 5–8 mice per group per experiment). *P < 0.05; **P < 0.001; ***P < 0.0001
