Fig. 4.

Effect of DaRT treatment on lung metastases. Lung metastases in mice bearing murine breast tumors treated by Ra-224-loaded wires. Treatment was applied to Balb/c mice bearing DA3 tumors (6–8 mm average diameter). a Fifty days post-treatment all mice were CT scanned for lung metastases. Tumor-bearing mice each treated with one Ra-224 wire, carrying activities in the range of 40–50 kBq (Ra-224 wire; n = 16). Inert—tumor-bearing mice treated with an inert wire were used as a control group (n = 16). P value (T test) DaRT vs. Inert <0.05. b Lung metastases in the mouse of control group is shown