Fig. 3.
In vitro combined effects of γδ T cells with ZOL on various cancer cells and their MHC class I expression. a Augmentation of the cytotoxic activity of the ex vivo-expanded γδ T cells by a low dose of ZOL (5 μM) in various cancer cell lines. In vitro cytotoxicity of γδ T cells from 3 healthy volunteers against SBC-5, HT-1080 UM-UC-3, 211H, and A549 was examined quantitatively by a standard 51Chromium (51Cr) releasing assay. Each value indicates the mean ± SEM (n = 6). b MHC class I expressions of human normal PBMNCs, UM-UC-3 and KU-7. The data shown are representative of 3 independent experiments