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In vivo anti-tumor activity of NK-92-scFv(Leu-16)-ζ cells. About 4 × 106 Raji cells were mixed with PBS, or NK-92-scFv(Leu-16)-ζ or parental NK-92 cells at an effector to target ratio of 5:1 as indicated and immediately injected subcutaneously into the flanks of NOD/SCID γ−/−c mice. Tumor growth was followed by caliper measurements. Mice were sacrificed when tumors reached 1.5 cm in diameter or when animals appeared to be in distress
