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IFN-γ and IL-6 mRNA, and protein in TIL during the P and the R phases. a P and the R phase TIL expressed both IFN-γ and IL-6 mRNA. The levels of IFN-γ mRNA in the P and the R phase TIL were not significantly different. However, the levels of IL-6 mRNA were higher in R phase than in P phase. b A similar result for the IL-6 protein was obtained by Western blotting, but the level of IFN-γ protein was higher in R phase than in P phase
