Fig. 2.
a Generation of resistance to P815 in DBA/2J mice. Eight DBA/2J mice were injected with 105 P815 cells subcutaneously into their right hind footpad (fp). 15 days later, these mice and two naïve mice were implanted with 105 P815 cells given id on their belly. Tumor progression of individual mice was assessed. 7/8 of the mice primed with the P815 resisted the challenge. b Generation of resistance to L5178Y in DBA/2J mice. Three mice were implanted with 103 L5178Y cells id on the belly on day 0. Sixty days after the initial implantation, these mice (closed squares), and three naïve age-matched control mice (open circles), were challenged with a normally lethal dose of 106 L5178Y tumor cells id on the belly