Fig. 4.

Killing of primary monocyte-derived macrophages by LC. Monocyte-derived macrophages (MDM) were generated from the blood of healthy dogs as described in “Methods”. After 7 days in culture, the MDM were treated with LC or PBS liposomes (L-PBS) and cell viability was analyzed 72 h later by MTT assay. Cell viability following incubation with 5% LC or 5% L-PBS at each time point was statistically compared using Student’s t test. Significant differences (p < 0.05) were denoted by *. The data shown are representative of three independent experiments