Fig. 6.

Adoptive transfer of splenocytes from immunized FVB-Tg mice. a Tumor-free periods of untreated FVB-Tg mice (No DLI, open circles, n = 14), or mice infused with whole (closed diamonds), CD4- (open squares) or CD8-depleted (closed squares) splenocytes (n = 10, 5, 7, respectively). *P < 0.05, **P < 0.01, and ***P < 0.005 compared with untreated mice. Tumor Index (b), the number of primary tumors (c), and lung metastases (d) in mice with or without adoptive transfer. *P < 0.05, CD4-, CD8-depleted compared to No DLI or Whole, and **P < 0.005, Whole compared to No DLI in (b) and (c). *P < 0.05 compared to other groups in (d)