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IL-10 Immunoadhesin constructs. a Schematic structures of IL10R1/IgG1Fc constructs, b Predicted three-dimensional molecular structure of human IL-10 homodimer with dimerized IL-10R1/IgG1Fc immunoadhesin (#4) Human IL-10, red and yellow; immunoadhesin (#4), blue and green. Three disulfide bonds of hinge region are presented with the CPK model (arrow)
