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The effect of antigen size on redirected lysis of transfected CHO cells by domain D3-specific BiTE antibody MCSP120. a CHO cell lines expressing EpCAM/MCSP fusion proteins or EpCAM alone were used as targets. b Dose–response analysis of redirected lysis for D3-specific BiTE antibody MCSP120 or EpCAM-specific BiTE antibody MT110 of CHO lines stably expressing fusion EpCAM/MCSP proteins or EpCAM. c Quantitation of assay results for maximal lysis and half maximum lysis (EC50)
