Table 1.
Immunofluorescence analysis of CEA-positive tumor cells after reaction with immune seraa
| Immunizations with | C15 cells | MC-38 cells |
|---|---|---|
| 3H1-QS21 | 30.1 | 4.6 |
| CEA-QS21 | 31.9 | 3.9 |
| 3H1-CpG | 26.2 | 3.1 |
| CEA-CpG | 27.0 | 2.8 |
| PBS | 4.0 | 2.3 |
| Preimmune sera | 2.2 | 2.1 |
| 8019 | 97.4 | 5.7 |
a Pre- and postimmune sera at 1:10 dilution were tested for binding on CEA-transfected C15 tumor cells or nontransfected parental MC-38 cells. Anti-CEA mAb 8019 at 1.0 μg was used as a positive control for C15 cells. Results are presented as percentage of positive cells. Data are a representation of two independent experiments