Table 4.
Dose level I | Dose level II | Dose level III | Dose level IV | Dose level V | |
---|---|---|---|---|---|
No. of patients | N = 3 | N = 1 | N = 4 | N = 5 | N = 2 |
Anemia | |||||
Grade 1/2/3/4 | –/–/–/– | –/–/–/– | 1/–/–/– | –/–/–/– | 1/–/–/– |
Leucocyte decrease | |||||
Grade 1/2/3/4 | –/–/–/– | –/–/–/– | –/–/–/– | –/–/–/– | –/1/–/– |
Lymphocyte decrease | |||||
Grade 1/2/3/4 | –/–/–/– | –/–/1/– | –/–/–/– | –/–/1/– | –/–/1/– |
Thrombocyte decrease | |||||
Grade 1/2/3/4 | –/–/–/– | –/–/–/– | –/–/–/– | –/–/–/– | 1/–/–/– |