Fig. 5.

Proapoptotic activity and cytotoxicity against gastric cancer cells lines. Proapoptotic activity of TIL-derived cancer peptide-specific T cell clones. To assess their ability to induce apoptosis in target cells, peptides-specific T cell clones were stimulated with mitogen (open squares) or medium alone (open squares) and cocultured with ⁵¹Cr-labeled Fas⁺ Jurkat cells. ⁵¹Cr release was then measured as index of apoptotic target cell death. Data of three representative clones are reported. Results represent mean values (±SD)