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Immune responses to the mouse part (open circle) and human part (crosses) of c-SN6j during and after six injections of c-SN6j into monkeys A – H. c-SN6j was given i.v. at a dose of 1 mg (monkeys A and B), 3 mg (monkeys C, D, G and H) or 10 mg (monkeys E and F) per kg BW. Monkeys G and H received i.v. administration of doxorubicin (0.275 mg/kg BW) in addition to c-SN6j. Preimmune serum of each monkey was included as a negative control in the assays
