Table 2.
Patient | HLA-A | HLA-B | HLA-C | HLA/antigen recognized |
---|---|---|---|---|
Positive TIL populations (n = 8)a | ||||
M88c | A*0201–0301 | B*1302–4002 | Cw*0602–0202 | B*1302/NA88-A |
M117 | A*0201–2402 | B*4402 | Cw*0501–0202 | A*0201/Melan-A/lage |
Cw*0501/lage | ||||
M134 | A*0201 | B*0801 | Cw*0701 | A*0201/Melan-A |
170c | A*0201–0301 | B*1402–4402 | Cw*0501–0802 | A*0201/Melan-A |
180c | A*0201–0101 | B*0702 | Cw*0602–0702 | A*0201/Melan-A |
M182 | A*0201 | B*1801–4402 | Cw*1203–0501 | A*0201/Melan-A |
M187 | A*0301 | B*1402–3503 | Cw*0401–0802 | Cw*0802/tyrosinase |
M213c | A*0101–0301 | B*3501 | Cw*0303–0401 | B*3501/MAGE-A2 |
Negative TIL populations (n = 4)b | ||||
M174c | A*2401–6801 | B*1401–4402 | Cw*0501–0802 | – |
M197c | A*0301 | B*1801–0702 | Cw*0702–1203 | – |
M177c | A*2402–2902 | B*0702 | Cw*0102–0802 | – |
M215c | A*2301–6801 | B*5801 | Cw*0202–0701 | – |
aTIL populations that recognized at least one of the tested antigens in one HLA context
bNo recognition of any HLA/antigen combination tested
cMelanoma patients with only one invaded lymph node at treatment