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. 2006 Jul 28;56(4):515–526. doi: 10.1007/s00262-006-0204-0

Table 5.

Amount of Melan-A-specific TIL infused to patients

Patients Total TIL (10−9)b Melan-A specific TIL (10−6)c Melan-A26–35 reactive lymphocytes (10−6)d
Melan-A/A2 specific TIL (n = 14)
RF-patients
M117 33.4 2,200 534
M182 3.7 740 252
M278 a 13.2 475 211
M134 22.5 450 270
M170a 9.5 190 38
M180a 9 180 54
M254 a 3.3 109 53
R-patients
M171 22 3,740 1,892
M199 8.3 556 108
M113 21.2 360 85
M263 a 12.6 315 101
M131 15.5 93 46
M204 26 52 26
M275a 9.2 37 28

aMelanoma patients bearing only one invaded lymph node

bTotal amount of TIL infused to patients

cEstimated amount of Melan-A specific TIL infused (detected by tetramer labeling). Patients indicated in italics have been patients enrolled in the open study

dEstimated amount of infused Melan-A26–35 reactive lymphocytes (detected by IFN-γ intracellular labeling in response to peptide pulsed-T2 cells)