Table 2.
Treatment | Untreated U937 % E : T contact (mean ± SD) | IL-4-treated U937 % E : T contact (mean ± SD) | IL-4-treated U937 % IGROV1 phagocytosis (mean ± SD) | FcεRI-transfected U937 % E : T contact (mean ± SD) |
---|---|---|---|---|
MOv18 IgE | 24.6 ± 14.2 | 51.4 ± 17.7 | 43.5 ± 17.0 | 24.2 ± 9.6 |
NIP IgE | 10.0 ± 7.5* | 13.9 ± 12.7*** | 10.6 ± 8.4*** | 7.2 ± 7.2*** |
MOv18 IgE + IDEC-152 Fab | 21.3 ± 16.3n/s | 26.1 ± 12.8** | 8.0 ± 5.4*** | 26.5 ± 11.4n/s |
MOv18 IgE + sFceRIa | 11.9 ± 8.9* | 15.7 ± 16.5** | 7.5 ± 6.8*** | 12.1 ± 8.6* |
Data were collected by counting effector : target cell contact or target cell phagocytosis per microscopic field and percent values were calculated. Mean values were calculated from ten microscopic fields for each sample condition and are shown ± SD. Student’s t-test was used to generate significance of values compared to samples given MOv18 IgE
n/s P > 0.05
* P < 0.05
** P < 0.005
*** P < 0.0005