Fig. 3.

Antibody-dependent cellular cytotoxicity (per cent lysis at an E:T ratio of 50:1) at baseline (day 1 before the 1st GM-CSF injection), day 5 and day 10 in CRC patients treated with GM-CSF and an anti-EpCAM MAb. The box, with a line indicating median, represents the 25th and 75th percentiles. The top and bottom whiskers represent the 90th and 10th percentiles, respectively. The outliers show the highest and lowest 10% of observed values. Wilcoxon signed rank test showed a significant decreased ADCC activity day 5 (no. of pairs = 18) and day 10 (no. of pairs = 16) compared to baseline