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Cohorts of patients according to GM-CSF dose in CRC patients treated with anti-EpCAM MAb and cytokines in relation to treatment cycle number
| Dose cohort of GM-CSF (μg/m2/day) | Treatment cycle number | |||
|---|---|---|---|---|
| I (n = 50) | II (n = 38) | III (n = 28) | IV (n = 25) | |
| 65 | 1 | 3 | 3 | 2 |
| 75 | 5 | 0 | 1 | 3 |
| 125 | 0 | 1 | 1 | 1 |
| 150 | 0 | 6 | 1 | 3 |
| 175 | 0 | 1 | 0 | 0 |
| 200 | 20 | 9 | 9 | 9 |
| 250 | 24 | 16 | 13 | 5 |
| 300 | 0 | 1 | 0 | 2 |
| 325 | 0 | 1 | 0 | 0 |
