Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
PGS R2 based on three sets of GWAS setups. “Main effects” were from a typical main effect GWAS, “GxAge” effects were from a GWAS with a SNP-age interaction term, and “Age stratified” GWAS had main effects only but were conducted in four age quartiles. PGS R2 was evaluated using two models: one with main effects only, and one with an additional PGS*Age interaction term.
