FIG. 4.
Downregulation of c-Myc during H-1 virus-induced apoptosis. (A) Western blot analysis of total proteins (70 μg/lane) extracted from H-1 virus-infected U937 cells (10 PFU/cell) at different times postinfection with anti-PARP (upper panel) or anti-c-Myc (lower panel) antibodies. (B) Northern blot analysis of total RNAs extracted from H-1 virus-infected U937 cells with c-myc (upper part)- or β-actin (lower part)-specific DNA probes. (C) Northern blot analysis of total RNAs extracted from H-1 virus-infected RU and U937 cells at the indicated times postinfection with c-myc (upper part)- or β-actin (lower part)-specific DNA probes.