Fig. 4.

Concentration of cytokines in serum of mice from all groups. Mice in both the vaccine and treatment groups had significantly increased expression of interleukin-2 and interferon γ (p < 0.05) compared to the control group. Moreover, mice with minor tumor load had increased expression in interleukin-2 (p = 0.102) and interferon γ (p < 0.05) compared with mice with heavy tumor load. No significant difference was found in concentration of IL-4 of all groups