Table 1.
Patient | Age/sex | Cancer type | Stage | Ras mutation | Prior treatment | Time from prior Tx to vaccine (months) |
---|---|---|---|---|---|---|
1 | 50/M | Colorectal | IV | Asp | Hemicolectomy, 5-FU/LV for 6 months, followed by resection of abdominal wall mass | 10 |
2 | 57/F | Colorectal | IV | Asp | 5-FU/LV for 12 months | 5 |
3 | 49/M | Pancreas | III | Asp | Whipple, XRT for 1 month, 5-FU/LV for 6 months | 12 |
4 | 64/M | Colorectal | III | Asp | Left hemicolectomy, 5-FU/LV for 6 months | 8 |
5 | 71/F | Pancreas | III | Asp | Partial pancreatectomy | 6 |
6 | 68/F | Pancreas | III | Asp | Whipple with IORT, concurrent XRT/5-FU for 5 weeks, gemcitabine for 6 months | 5 |
7 | 49/M | Pancreas | III | Val | Whipple, 5-FU for 1 month, then concurrent XRT/5-FU for 1 month, then 5-FU for 3 months | 4 |
8 | 56/F | Colorectal | III | Asp | Hemicolectomy, 5-FU/LV for 6 months | 5 |
9 | 38/M | Colorectal | IV | Asp | Right hemicolectomy, camptosar/5-FU/LV for 6 months, cervical lymph node metastectomy, cervical XRT | 1.5 |
10 | 67/M | Pancreas | II | Val | Whipple | 1.5 |
11 | 57/F | Colorectal | III | Asp | Hemicolectomy, 5-FU/LV for 6 months | 10 |
12 | 43/F | Colorectal | III | Asp | Segmental resection of the transverse colon, 5-FU/LV for 6 months | 2 |
M male, F female, Asp patient has the ras mutation in codon 12 Gly to Asp, Val patient has the ras mutation in codon 12 Gly to Va, 5-FU 5-fluorouracil, LV leucovorin, XRT radiotherapy, IORT intraoperative radiotherapy