Survival HRs and 95% CIs based on the three trials with quality scores of A+++ and A++. MF mitomycin C plus futraful, FT futraful, CQ carbazilquinone, MHCFU mitomycin C plus HCFU, MFU mitomycin C plus 5-fluorouracil, MT mitomycin C plus tegaful, T tegaful