Fig. 6.

Comparing vaccine efficacy of DCh5T4/DCh5T4, Adh5T4/Adh5T4, DCh5T4/Adh5T4 and Adh5T4/DCh5T4 in active therapy. Adh5T4/DCh5T4, DCh5T4/DCh5T4 and Adh5T4/Adh5T4 can delay tumour progression, but DCh5T4/Adh5T4 provides no survival advantage. Groups of seven mice were challenged with tumour on day 0 and then treated on day 7 and 14 with the above treatment and tumour growth monitored until the product of perpendicular tumour diameter reached 1.24 cm². The data is presented as a Kaplan–Meier survival curves and is representative two independent studies. Log Rank test was used to determine whether vaccine mediated survival was significant versus respective control vaccinations