Fig. 3.

Target cells are more efficiently sensitized for lysis by modified than by non-modified peptide. Spleen cells derived from the HHD transgenic mice immunized with mp30 pulsed DCs were studied for their capacity to lyse EL4-A2K^b cells pulsed with a dose titration of mp30–38 versus p30-38 peptide. The effector cells and target cells pulsed with different concentration of peptides were cultured at ratio of 50:1 for 4 h. Filled squares are EL4-A2K^b pulsed with mp30, open squares are EL4-A2K^b pulsed with p30. Error bars represent standard deviations