Fig. 3.

Lysis of human cancer cell lines by CTL clones. Cell lysis of the HLA-A2 positive melanoma cell lines FM76, FM92, ESTDAB-001, 006, 014, 017, 019, 021, 026, 027, 028, 029, 033, 100, and 117 by the a MART-1_27–35 and the b Bcl-2_208–217-specific CTL clones. c Killing of non-melanoma cell lines (i.e., the HLA-A2 positive breast cancer cell lines MDA-MB-132 and CAMA-1, the HLA-A2 positive colon cancer cell line HCT-116, and the HLA-A2 negative breast cancer cell line ZR-75-1) by the MART-1_27–35 and Bcl-2_208–217-specific CTL clones. All ⁵¹Cr-release assays were performed in three E:T ratios