Table 1.
Experimental groups and their chimerism
| Groups | Description | n | Transplantation | Chimerisma | |||
|---|---|---|---|---|---|---|---|
| BMCs | Thymus | H-2Kb | H-2Kd | H-2Kk | |||
| 1 | Non-treated | 8 | (–) | (–) | 0.1 ± 0.1 | 99.8 ± 0.2 | ND |
| 2 | Syn-BMT | 11 | BALB/c | (–) | 0.2 ± 0.1 | 97.8 ± 0.2 | ND |
| 3 | Syn-BMT + Syn-TT | 11 | BALB/c | BALB/c | 0.7 ± 0.3 | 98.2 ± 0.3 | ND |
| 4 | Syn-BMT + Allo-TT | 13 | BALB/c | B6 | 0.5 ± 0.5 | 99.5 ± 0.2 | ND |
| 5 | Allo-BMT | 13 | B6 | (–) | 98.8 ± 0.2 | 0.2 ± 0.2 | ND |
| 6 | Allo-BMT + Allo-TT | 12 | B6 | B6 | 99.6 ± 0.5 | 0.2 ± 0.3 | ND |
| 7 | Allo-BMT + 3rd party-TT | 12 | B6 | C3H | 96.7 ± 0.7 | 0.7 ± 0.5 | 0.9 ± 0.7 |
The categorizing of each group is described in “Materials and methods”
aChimerism was determined in spleen cells of the mice in the non-treatment group (group 1, n = 4) 2–3 weeks after the tumor reached >4 cm2 in size and in the mice in the BMT groups (groups 2–7, n = 4–6) 4–5 weeks after transplantation