Assessment of cytolytic activity of Aurora-A161–175 and Aurora-A233–247-specific HTL clones. The DR9-restricted, Aurora-A161–175-specific HTL clone 4E (a) and the Aurora-A233–247-specific, DR53-restricted HTL clone 5 (b) were evaluated for their capacity to kill Aurora-A expressing, DR9+ and DR53+ tumor cells (5637 and SW839) or Aurora-A expressing, DR9 negative, DR53 negative tumor cells (MCF7, negative control). Points means of triplicate determinations, bars SD. Points without bars had SD < 10% the value of the mean