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. 2008 Aug 15;58(3):317–324. doi: 10.1007/s00262-008-0576-4

Table 1.

Chemotherapy can augment immunotherapy by multiple pathways

Drugs References
1. Increased antigen cross-presentation Gemcitabine [33, 47, 48]
2. Activation of dendritic cells Paclitaxel [47, 48, 69]
3. Homeostatic proliferation Alkylating agents, fludarabine [42, 49, 54]
4. Increased homing to tumors Gemcitabine, antivascular flavonoids [33, 48, 62]
5. Inhibition of immunosuppressive cells Gemcitabine, cyclophosphamide, taxanes [31, 35, 42, 47, 48, 56, 60]
6. Upregulation of recognition molecules Cisplatin, 5-FU, 5-aza-2′ deoxycitidine [33, 42, 50, 59]