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. 2009 Nov 20;59(5):747–757. doi: 10.1007/s00262-009-0795-3

Fig. 2.

Fig. 2

Detection of T cell responses specific for Top2α and survivin in mice vaccinated with DC pulsed with MC-38 tumor lysate. Top2α-specific immune responses were measured with the ELISPOT assay using DC, CEARNA/DC, Top2αCRNA/DC, survivinRNA/DC (SuvRNA/DC), or MC-38 tumor lysate/DC (MC38TL/DC) as the target cells. Results are given as the mean number of IFN-γ spots per 5 × 104 splenocytes from individually tested mice ±SE. The statistical significance was evaluated with a t test of the pooled results of two experiments. *P < 0.05 (DC vs. each group)