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. 2010 Jun 20;59(10):1531–1541. doi: 10.1007/s00262-010-0880-7

Table 1.

Effect of MZF on the expression of DC maturation markers

Maturation marker MZF concentration (μg/ml) LPS
0 100 200 400
CD80
 Percentage of positive cells 31.96 ± 0.58 34.91 ± 0.62* 36.34 ± 0.36* 44.35 ± 0.38* 66.33 ± 0.39*
 MFI 74.68 ± 2.08 70.28 ± 2.20 75.04 ± 1.91 102.88 ± 2.97* 165.98 ± 4.43*
CD86
 Percentage of positive cells 35.20 ± 2.94 42.49 ± 0.35 47.16 ± 1.14* 61.29 ± 8.47* 72.97 ± 0.78*
 MFI 55.56 ± 6.81 88.70 ± 4.04* 92.01 ± 2.03* 109.76 ± 2.26* 186.50 ± 2.25*
CD83
 Percentage of positive cells 10.13 ± 0.38 13.06 ± 1.13 17.94 ± 0.43* 24.69 ± 0.59* 24.83 ± 0.49*
 MFI 4.98 ± 0.08 5.99 ± 0.25* 6.43 ± 0.20* 8.72 ± 0.54* 9.50 ± 0.59*
MHC class II
 Percentage of positive cells 28.25 ± 0.43 29.06 ± 0.71 32.69 ± 0.69* 43.95 ± 0.24* 40.17 ± 0.22*
 MFI 131.59 ± 2.85 143.05 ± 2.90* 144.75 ± 3.17* 179.11 ± 1.97* 182.85 ± 3.97*

DCs (1 × 106 cells/ml) were stimulated with MZF (0–400 μg/ml) or LPS (100 ng/ml) for 24 h. The values are percentages of DCs (CD11c+ cells) expressing indicated markers and the mean fluorescence intensity (MFI). Values are expressed as mean ± SE (n = 3)

p < 0.05 versus control